Journal of natural medicinesCarbazolesHumansGlioblastomaBlood-Brain BarrierNeoplastic Stem Cells
Antiproliferative activity against glioblastoma-derived cancer stem cells and blood-brain-barrier permeability of carbazole derivatives from Murraya plants and related synthetic compounds.
Kouta Ugawa, Raiki Yamamura, Kaori Yajima, Tomoe Ohta, Seikou Nakamura
Published: 202510.1007/s11418-025-01956-w
Abstract
Carbazoles exhibit various pharmacological activities, including antitumor activity. Eustifoline-B is a carbazole from Murraya (Rutaceae) plants that exhibited strong antiproliferative activity against cancer stem cells (CSCs) that were established f…
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