Journal of natural medicinesHumansUterine Cervical NeoplasmsEpithelial-Mesenchymal TransitionFemaleAnimals
Digoxin targets BHLHE40 to inhibit epithelial-mesenchymal transition in cervical cancer cells via downregulation of ANGPTL3.
Canyi Li, Penghua Luo, Lin Tang, Yongqiang Yang, Long Rao, Lijun Zhong
Published: 202610.1007/s11418-025-01947-x
Abstract
This study aims to investigate the mechanism of action of BHLHE40 and its targeted drug, digoxin, in cervical cancer. The clinical significance of BHLHE40 was evaluated in cervical cancer samples using the UALCAN and Human Protein Atlas databases. Th…
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