GeroScience
Angiotensin II induces sex-specific ventricular remodeling in aging C57Bl/6 mice.
Ninh Khuong, Manish Mishra, Shubham Banga, Susan E Howlett
Published: 202510.1007/s11357-025-01924-y
Abstract
Renin-angiotensin system (RAS) activation in heart failure (HF) increases circulating angiotensin II (AII). This increases blood pressure (BP) and promotes adverse ventricular remodeling that makes HF worse. Although human HF increases with age and d…
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