Molecular imaging and biology
PET Imaging of CD38 and IND enabling studies of [89Zr]Zr-DFO-Isatuximab.
Brian D Wright, Hailey A Houson, Solana Fernandez, Kadir Gultekin, Jonathan E McConathy, Smith Giri, Suzanne E Lapi
Published: 202510.1007/s11307-025-02062-9
Abstract
BACKGROUND: CD38 is an excellent biomarker and therapeutic target for multiple myeloma due to its high expression on cancerous cells in comparison to healthy cells. PURPOSE: We aimed to adapt Isatuximab as a PET imaging agent to detect CD38 positive…
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