Virus genes
The disappearance of ORF8 in human-adapted coronaviruses: the Cheshire cat paradigm.
Philippe Colson, Anthony Levasseur, Hervé Chaudet, Christian Devaux, Jacques Fantini, Pierre Pontarotti, Didier Raoult
Published: 202510.1007/s11262-025-02196-6
Abstract
We studied the fate of a gene called ORF8 in different coronaviruses species during their passage to humans. We showed that this gene harbored stop codons in many epidemic SARS-CoV-2 variants in humans and in up to 86% of SARS-CoV-2 circulating in 20…
Preview only. Read the full abstract at the source