International urology and nephrology
Metformin use linked to decreased risk of pelvic organ prolapse: insights from NHANES data.
Zhe Du, Zhao Tian, Linru Fu, Xiuqi Wang, Xinyi Wang, Tao Xu, Zhijing Sun
Published: 202510.1007/s11255-025-04849-9
Abstract
PURPOSE: Preclinical evidence suggests that metformin may mitigate pelvic organ prolapse (POP) by altering the gene expression of human vaginal fibroblasts in a beneficial direction, but clinical validation is lacking. This study aimed to explore the…
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