International journal of clinical pharmacy
Exploring the effects of renal and cardiac functions on the pharmacokinetics of vancomycin in patients undergoing cardiac surgery: a population pharmacokinetic analysis.
Yinglong Ding, Ling Xue, Qiong Qin, Haoyue Huang, Yihuan Chen, Han Shen, Yanqiu Hu, Yupeng Chen, Liyan Miao, Zhenya Shen
Published: 202610.1007/s11096-025-02077-w
Abstract
INTRODUCTION: Vancomycin is a glycopeptide antibiotic commonly prescribed to treat severe gram-positive infections; however, it has a narrow therapeutic range and potentially induces nephrotoxicity following overdosing. Most studies have revealed tha…
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