Pharmaceutical research
Investigation of Phytol as an Inhibitor of the Efflux Pump (QacA/B) in Staphylococcus aureus: in silico and in vitro Studies.
José Weverton Almeida-Bezerra, Carlos Alonso Leite Dos Santos, Saulo Almeida Menezes, Cícera Datiane de Morais Oliveira-Tintino, Rafael Pereira da Cruz, Adrielle Rodrigues Costa, Janaína Esmeraldo Rocha, Daniel Sampaio Alves, Simone Galdino de Sousa, Ewerton Yago de Sousa Rodrigues, Gabriel Gonçalves Alencar, José Maria Barbosa Filho, Viviane Bezerra da Silva, Saulo Relison Tintino, Irwin Rose Alencar de Menezes
Published: 202510.1007/s11095-025-03991-4
Abstract
OBJECTIVE: Staphylococcus aureus is a microorganism that can behave as a commensal or as a life-threatening pathogen. Its remarkable capacity to acquire resistance to antimicrobial agents, particularly through mechanisms such as efflux pumps, places…
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