Pharmaceutical research
Aerosol Delivery of Polyelectrolyte Surfactant-Antimicrobial Nanoparticles to the Lungs.
Yadiel Varela Soler, Amanda S Padilla-López, Sughosha Rao, Leonardo Calderon, Gediminas Mainelis, Olga Garbuzenko, Tamara Minko, David I Devore, Charles M Roth
Published: 202610.1007/s11095-025-03985-2
Abstract
BACKGROUND: Lung infections affect over 80% of adults with cystic fibrosis, with Pseudomonas aeruginosa being a leading pathogen. Although antibiotics are frequently nebulized as standard treatments, the physicochemical environment of the diseased lu…
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