Pharmaceutical researchHumansLiposomesMelanomaSkin NeoplasmsDrug Liberation
Preparation and Characterization of Novel Pan-RAS Inhibitor Loaded Ultraflexible Liposomes for the Topical Prevention or Treatment of Skin Melanoma.
Shivani A Dave, Adam B Keeton, Gary A Piazza, Anthony J Di Pasqua
Published: 202510.1007/s11095-025-03950-z
Abstract
PURPOSE: There are no preventive and few therapeutic options for melanoma, an aggressive skin cancer, especially in situations where N-Ras mutations are present. The new pan-Ras inhibitor ADT-007 has promise for treating melanoma. This study aimed to…
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