Neurochemical researchAnimalsEpilepsyTemporal LobeFibronectinsHippocampus
Altered Fibronectin-α5β1 Integrin-Src Signalling Pathway Drives Network Hyperexcitability in the Hippocampal Formation and Anterior Temporal Lobe in Temporal Lobe Epilepsy.
Nitin Yadav, Priya, Neha Dixit, Sneha Anand, Jyotirmoy Banerjee, Manjari Tripathi, P Sarat Chandra, Ramesh Doddamani, M C Sharma, Sanjeev Lalwani, Fouzia Siraj, Aparna Banerjee Dixit
Published: 202610.1007/s11064-025-04656-9
Abstract
Fibronectin (FN1), a vital extracellular matrix protein, has been reported to be elevated in blood and cerebrospinal fluid in epileptic patients exhibiting recent seizure activity. A transcriptomic study from MTLE-HS patients has identified FN1 as a…
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