Neurochemical researchAnimalsCholinesterase InhibitorsAmyloid beta-PeptidesHippocampusNeuroprotective Agents
Targeting Amyloid Toxicity: Novel Cholinesterase Inhibitors Protect Hippocampal Cells from Amyloid Peptide-Derived Death.
Sona Buloyan, Anahit Poghosyan, Hayk Harutyunyan, Hermine Yeritsyan, Marina Sargsyan, Armen Hovhannisyan, Vigen Topuzyan, Hrachik Gasparyan
Published: 202510.1007/s11064-025-04592-8
Abstract
Alzheimer's disease (AD) is one of the most common neurodegenerative disorders. The accumulation of amyloid-beta (Aβ) deposits in the brain is considered a major cause of the disease. Acetylcholinesterase (AChE) plays a unique role in AD pathogenesis…
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