Molecular biology reportsHumansMaleProstatic NeoplasmsSerine EndopeptidasesMiddle Aged
TMPRSS2 rs12329760 variant as a prognostic marker for prostate cancer progression.
Khaoula Elghazali, Mouad Najih, Zineb Sakhi, Youssef Ennaji, Abdelilah Laaraqui, Rida Tagajdid, Abdessamad Amine, Moulay Mustapha Ennaji
Published: 202610.1007/s11033-026-11442-5
Abstract
BACKGROUND: TMPRSS2, a transmembrane serine protease and common partner in oncogenic TMPRSS2-ERG fusions, is regulated by androgen receptors and is implicated in prostate tumorigenesis. The nonsynonymous SNP rs12329760 (C > T; Val160Met) has been hyp…
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