Molecular biology reportsHumansImmunityInnateReceptorsChimeric Antigen
Redefining cell therapy: CAR-engineered innate immune cells to conquer solid and hematologic malignancies.
Ashik Anil Mathew, Ronak Raheja, Kannan Ramalingam
Published: 202610.1007/s11033-025-11407-0
Abstract
Chimeric antigen receptor (CAR) technology has revolutionized cancer therapy, yet its full potential remains untapped within the innate immune system. Beyond CAR-T cells, a growing cadre of MHC-independent effectors, including NK cells, macrophages,…
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