Molecular biology reportsHumansEpilepsyTemporal LobeNeurosteroidsAnimals
Molecular mechanisms of neurosteroids in temporal lobe epilepsy: current insights and therapeutic perspectives.
Zainah Al-Qahtani, Hayder M Al-Kuraishy, Nawar R Hussain, Huda J Waheed, Ali I Al-Gareeb, Ali K Albuhadily, Aya M Mustafa, Mubarak Alruwaili, Athanasios Alexiu, Marios Papadakis, Gaber El-Saber Batiha
Published: 202510.1007/s11033-025-11238-z
Abstract
Neurosteroids (NSs) are endogenous progesterone derivatives that act as natural allosteric modulators of GABAA receptors, exerting distinct effects from conventional receptor agonists. They play critical roles in modulating neuronal excitability, co…
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