Molecular biology reportsInflammasomesNLR FamilyPyrin Domain-Containing 3 ProteinHumansAnimals
Activation and regulation of NAIP/NLRC4 and NLRP3 inflammasomes during Salmonella infection: mechanisms and therapeutic implications.
Yeling He, Dandan Ding, Jiayin Guo, Hui Sun, Jing Yang
Published: 202510.1007/s11033-025-11166-y
Abstract
Inflammasomes constitute a critical component of host defense against Salmonella infection, among which the NAIP/NLRC4 and NLRP3 complexes serve as the two principal signaling platforms. The NAIP/NLRC4 inflammasome functions as a rapid-response senso…
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