Molecular diversity
Synthesis of redox-responsive polyurethane nanocapsules for small-molecule delivery and antitumor evaluation on human leukemia K562 cells.
Na Shi, Mengting Liu, Dandan He, Nianlin Feng, Yi Zhang, Dandan Liu, Chenchen Li, Zhenchao Wang
Published: 202610.1007/s11030-026-11466-w
Abstract
High concentrations of glutathione (GSH) in the tumor microenvironment (TME) represent a promising target for the development of polyurethane (PU)-based redox-responsive drug delivery systems. A series of 3-indolopyrazole acetamide derivatives were d…
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