Molecular diversity
A novel matrine derivative B10 exerts its anti-liver cancer activity in vitro and in vivo via targeting FGFR3/PI3K/AKT signaling pathway.
Xingdong Wang, Yuxin Xie, Zhouxing Hu, Siyi Wang, Manqi Li, Lichuan Wu, Jun Jiang, Lisheng Wang
Published: 202610.1007/s11030-025-11460-8
Abstract
Natural products represent a cornerstone in anticancer drug discovery owing to their structural diversity and unique bioactivities. Among them, matrine-a principal alkaloid derived from the traditional Chinese medicine Sophora flavescens-has attracte…
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