Molecular diversity
Advances in 1,3,4-thiadiazole-based cholinesterase inhibitors: toward novel therapeutics for Alzheimer's disease.
Moksh Shah, Kripa Patel, Utkarsha Kulkarni, Mange Ram Yadav, Ashish Patel, Afzal Nagani
Published: 202610.1007/s11030-025-11458-2
Abstract
Alzheimer's disease (AD) is a progressive neurodegenerative disorder in which cholinergic dysfunction plays a central role. Inhibition of acetylcholinesterase and butyrylcholinesterase remains a validated therapeutic approach for managing AD symptoms…
Preview only. Read the full abstract at the source