Molecular diversity
Targeting histidine biosynthesis in Acinetobacter baumannii: structure-based discovery of natural inhibitors of ATP-phosphoribosyltransferase.
Anamika Singh, Mansi Tanwar, Tej P Singh, Sujata Sharma, Pradeep Sharma
Published: 202510.1007/s11030-025-11409-x
Abstract
The increasing threat of multidrug-resistant Acinetobacter baumannii infections demands the development of novel antimicrobials targeting unexplored bacterial pathways. ATP phosphoribosyltransferase (ATP-PRT), the first and rate-limiting enzyme in th…
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