Molecular diversity
Deep learning-driven QSAR and micro-scale MD simulation-guided strategy reveals non-toxic human HGFR inhibitors.
Muhammad Waleed Iqbal, Muhammad Ali Raza, Xinxiao Sun, Xiaolin Shen, Qipeng Yuan
Published: 202510.1007/s11030-025-11380-7
Abstract
Hepatocyte Growth Factor Receptor (HGFR) overexpression plays a critical role in ovarian cancer progression by promoting cell proliferation, survival, and metastasis. Despite the therapeutic potential of existing HGFR inhibitors, such as crizotinib,…
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