Metabolic brain diseaseAnimalsOxidopaminePC12 CellsRatsAutophagy
Paeony root prevents 6-hydroxydopamine-induced neurotoxicity by regulating autophagic dysfunction via AKT signaling in Parkinson's disease models.
Yujin Choi, Eugene Huh, In Gyoung Ju, Hanbyeol Lee, Jin Hee Kim, Seungmin Lee, Siyeon Park, Minsik Choi, Young Pyo Jang, Hi-Joon Park, Myung Sook Oh
Published: 202510.1007/s11011-025-01764-x
Abstract
Parkinson's disease (PD) is a neurodegenerative disease that primarily affects motor function. Dopaminergic cell death occurs progressively in the PD brain and autophagic dysfunction is critically implicated in the neuronal death. Therefore, modulati…
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