Metabolic brain diseaseAnimalsMinocyclineMaleMicrogliaMice
Minocycline inhibits microglial activation and mitigates compulsive and anxiety-like behaviors induced by a high-refined carbohydrate diet in male BALB/c mice.
Nícia Pedreira Soares, Anna Paula Marçal, Amanda Carla Oliveira, Rayssa C Briânis, Rafaela Pinto Coelho Santos, Adaliene Verssiani Matos Ferreira, Daniele Cristina de Aguiar
Published: 202510.1007/s11011-025-01731-6
Abstract
Consumption of a high-carbohydrate (HC) diet, which is commonly associated with obesity, has been linked to anxiety-like and compulsive behaviors. This association is predominantly attributed to chronic low-grade inflammation, which affects both the…
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