Molecular and cellular biochemistry
Growth differentiation factor 11 attenuates doxorubicin-induced cardiotoxicity by inhibiting myocardial pyroptosis and oxidative stress.
Jiangping Ye, Yehong Liu, Feng Xu, Ying Sheng, Dongxia Xu, Rikang Yuan, Xinyi Hu, Yuting Zhou, Tianhui Jin, Ting Ye, Gangjun Zong
Published: 202510.1007/s11010-025-05416-7
Abstract
Doxorubicin (DOX) is limited in clinical application because of its cardiotoxicity. One of the key elements of DOX-induced cardiotoxicity is pyroptosis, a kind of programmed cell death brought on by immunity and followed by inflammatory response. Gro…
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