Journal of computer-aided molecular designHumansCarcinomaHepatocellularLiver NeoplasmsMachine Learning
Synergistic approach utilizing bioinformatics, machine learning, and traditional screening for the identification of novel CSK inhibitors targeting hepatocellular carcinoma.
Yang Lu, Bizhi Li, Xiaoli Zheng, Lei Xu, Linghui Zeng, Chong Zhang, Jiankang Zhang
Published: 202510.1007/s10822-025-00703-3
Abstract
The overexpression or activation of C-terminal Src kinase (CSK) has been recognized as a pivotal factor in the progression of hepatocellular carcinoma (HCC), positioning CSK as a promising therapeutic target. Despite this potential, no CSK-specific i…
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