Journal of computer-aided molecular designHumansAntineoplastic AgentsQuinazolinesMolecular Docking SimulationMolecular Dynamics Simulation
In vitro and in silico evaluation of synthesized 4-Anilinoquinazoline derivatives as potential anticancer agents.
Yusuf Eka Maulana, Ade Danova, Chanat Aonbangkhen, Jaruwan Chatwichien, Sutthida Wongsuwan, Elvira Hermawati, Warinthorn Chavasiri, Anita Alni
Published: 202510.1007/s10822-025-00680-7
Abstract
Twenty-three 4-anilinoquinazoline derivatives were successfully synthesized, including six new compounds (8, 9, 12, 17, 19, 20) and seventeen known compounds. Seventeen derivatives (10-26) were evaluated for cytotoxic activity against three cancer ce…
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