International ophthalmologyAnimalsIntravitreal InjectionsRatsArmadillo Domain ProteinsRNA
Intravitreal injection of SARM1 siRNA in TNF-induced optic nerve degeneration.
Yasushi Kitaoka, Chihiro Tsukahara, Naoki Fujita, Ibuki Arizono, Mizuki Otsubo, Kana Sase
Published: 202510.1007/s10792-025-03808-8
Abstract
PURPOSE: Intravitreal injections of some drugs such as anti-VEGF antibodies are available for certain human ocular diseases. Meanwhile, inhibition of SARM1 has been reported to exert neuroprotection in several neurodegenerative disease models. The ai…
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