Inflammopharmacology
Targeting protein kinase C signaling cascades in alzheimer's disease: emerging neuroprotective roles of aurothioglucose.
Shiv Kumar Kushawaha, Kanika Vashisht, Himanshu Kumar, Mahendra Singh Ashawat, Ashish Baldi
Published: 202510.1007/s10787-025-02077-2
Abstract
Protein Kinase C (PKC), a zinc-dependent signaling enzyme pivotal for neuronal survival and synaptic plasticity, has emerged as a central player in the pathogenesis of Alzheimer's disease (AD). Dysregulated PKC activity contributes to amyloid-β accum…
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