Inflammopharmacology
Kynurenine pathway in Parkinson's disease: pathophysiological roles and therapeutic interventions.
Aganta Chakraborty, Priya Chaudhary, Joy Das, Utpal Bhui, Khadga Raj Aran, Md Sadique Hussain, Sumel Ashique, Biplab Debnath
Published: 202510.1007/s10787-025-02052-x
Abstract
Several disrupted metabolic pathways contributed to the development of Parkinson's disease (PD). Progressive death of dopamine (DA) neurons in the substantia nigra pars compacta, abnormal aggregation of α-synuclein fibrils, and inflammation of the ne…
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