Inflammopharmacology
Diphenyleneiodonium exhibits protective effects against both nociception and gastrointestinal inflammation in vivo.
Ahmed Kouki, Abdelaziz Souli, Dorsaf Bouzazi, Salwa Bouabdallah, Wafa Ferjani, Pham My-Chan Dang, Mossadok Ben-Attia, Jamel El-Benna
Published: 202510.1007/s10787-025-02046-9
Abstract
Reactive oxygen species (ROS) and nitrogen-derived oxidants, such as nitric oxide (NO), are produced by immune cells through the activation of nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOXs) and nitric oxide synthases (NOS), respe…
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