Journal of molecular histologyAnimalsFerroptosisSevofluraneRatsNuclear Receptor Coactivators
Sevoflurane-induced ferroptosis in developing neurons mediated by the NCOA4-ferritinophagy-GPX4 pathway.
Cheng-Yi Lao, Wei-Xin Dai, Jie-Chao Zhou, Rui-Ping Huang, Huan Feng
Published: 202610.1007/s10735-025-10712-z
Abstract
Sevoflurane is a cornerstone of pediatric anesthesia but poses risks for neurodevelopmental toxicity. While dysregulation of iron metabolism and autophagy have been implicated, the precise molecular link, particularly the role of NCOA4-mediated ferri…
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