Fish physiology and biochemistryAnimalsZebrafishLiverAndrostadienesTumor Suppressor Protein p53
Exemestane induces liver toxicity in zebrafish larvae by upregulating the p53 signaling pathway.
Weirong Li, Xiying Zhou, Wanqing Chen, Weitao Hu, Ziang Wang, Zhonghao Xiao, Wenbin Yuan, Jianping Lian, Juhua Xiao, Zigang Cao, Shouhua Zhang, Bin Wang
Published: 202510.1007/s10695-025-01588-7
Abstract
Exemestane is an aromatase inhibitor that is used for the treatment of breast cancer. The aim of this study was to evaluate the effects of exemestane on liver development of zebrafish embryos. In this study, zebrafish embryos at 72 h post-fertilizati…
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