European journal of epidemiology
Integration of latent factor analysis into multivariable Mendelian randomization.
Yuankai Zhang, Roby Joehanes, Tianxiao Huan, Lukas M Weber, Qiong Yang, Kathryn L Lunetta, Daniel Levy, Chunyu Liu
Published: 202610.1007/s10654-025-01324-8
Abstract
Mendelian randomization has emerged as a powerful tool for exploring causal relationships in observational studies by using genetic variants as instrumental variables. While multivariable Mendelian randomization extends this approach to simultaneousl…
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