Digestive diseases and sciences
Diagnostic Performance of Metagenomic Next-Generation Sequencing (mNGS) and Culture in Infected Pancreatic Necrosis: A Systematic Review and Meta-Analysis.
Aizaz Ali, Asad Iqbal Khattak, Dikshit Chawla, Fariha Hasan, Hafsa Khan, Muhammad Abdullah Ali, Abdul Moeez, Sana Tanveer, Ubaidullah, Muhammad Jibran Afridi, Jibran Ikram, Saad Hayat, Fatima Zehra Shah, Ahmed Nadeem, Muhammad Ahmad Nadeem
Published: 202510.1007/s10620-025-09474-1
Abstract
BACKGROUND: Infected pancreatic necrosis (IPN) is a severe complication of acute pancreatitis, requiring prompt diagnosis. Conventional microbial culture, the current gold standard, has limitations in sensitivity and turnaround time. Metagenomic next…
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