Digestive diseases and sciences
Deciphering Cancer Evolution Through Genomic Profiling of Patient-Derived Xenograft Together with Matched Primary Gallbladder Cancer.
Vipin Yadav, Ragini Kilambi, Archana Rastogi, Deepti Sharma, Perumal Nagarajan, Varun Suroliya, Anupam Bhattacharya, Vaishali Yadav, Pramod Gautam, Manju Kashayp, Manoj Kumar Kashyap, Vanya Garg, Anupama Kumari, Nirupama Trehanpati, Gayatri Ramakrishna
Published: 202510.1007/s10620-025-09471-4
Abstract
BACKGROUND: Gallbladder cancer has a poor prognosis due to its aggressive nature and late detection. Adenosquamous subtypes are rare and poorly characterized at the molecular level. Patient-derived xenograft (PDX) models preserve tumor heterogeneity…
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