Cellular and molecular neurobiology
Intermittent Propofol Exposure Induces Neurodevelopmental Alterations in Human Brain Organoids.
Sudena Wang, Chloe Hall, Yong Wang, Leonie Link, Yi Zhang, Alexander Schlägel, Cora Wunder, Christopher Patzke, Matthias Klein, Thomas Mittmann, Michael K E Schäfer
Published: 202610.1007/s10571-026-01673-2
Abstract
The administration of anaesthesia during pregnancy may have implications for fetal brain development. This study used H1 embryonic stem cell-derived human brain organoids (HBOs) to investigate effects of intermittent propofol exposure (IPE). HBOs wer…
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