Cardiovascular drugs and therapy
Natriuretic Peptides as Multisystem Regulators: From Clinical Biomarkers to Therapeutic Targets in Cardio-immunology.
Jathniel Panneflek, Mahmoud Barbarawi, Yasitha Kakarlapudi, Zaid Barbarawi, Béatrice Lauzea, Manolo Meraz-Torres
Published: 202510.1007/s10557-025-07821-y
Abstract
PURPOSE: Natriuretic peptides (NPs) ANP, BNP, and CNP extend beyond biomarkers of wall stress to regulators of cardiovascular, renal, metabolic, and immune pathways via cGMP-PKG signaling. We synthesize mechanistic and translational evidence, highlig…
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