BiogerontologyCurcuminTOR Serine-Threonine KinasesAnimalsParticulate MatterCellular Senescence
Curcumin attenuates PM2.5-triggered pulmonary senescence via the mTOR/S6K1 signaling pathway.
Kai Liu, Meng Shi, Xin Li, Xiaoli Zeng, Xiaoju Liu
Published: 202610.1007/s10522-025-10383-z
Abstract
Exposure to fine particulate matter (PM2.5) triggers pulmonary inflammation and oxidative stress, which can lead to cellular senescence and a decline in lung function. Curcumin, a yellow polyphenol derived from the rhizome of Curcuma longa, is tradit…
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