BiogerontologyHumansAgingCellular SenescenceSingle-Cell AnalysisBone Marrow
Integrated single-cell multi-omics profiling reveals a senescence-associated hematopoietic landscape and regulatory network in aging bone marrow.
Guoyang Zhang, Weixuan Lin, Linghuan Guo, Ziyun Li, Yu Xiang, Luo Wang, Xiaoyu Yan
Published: 202510.1007/s10522-025-10352-6
Abstract
Bone marrow exhibits functional decline, yet cellular heterogeneity and molecular mechanisms remain unclear due to limitations of traditional research methods. This study aims to characterize age-related changes and identify key drivers in bone marro…
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