Bulletin of experimental biology and medicineMycobacterium tuberculosisHydrazonesMicrobial Sensitivity TestsAntitubercular AgentsBacterial Proteins
Adaptation of Mycobacterium tuberculosis to a New Aroylhydrazone Derivative In Vitro and Possible Role of Rv3755c Gene.
I V Mokrousov, V Angelova, S Dimitrov, S A Chekrygin, V Valcheva
Published: 202510.1007/s10517-025-06507-7
Abstract
We evaluated the response of Mycobacterium tuberculosis to exposure to a new aroylhydrazone derivative using the in vitro mutagenesis followed by genomic analysis of a resistant variant. The compound N'-[(E)-(5-methoxy-1H-indol-3-yl)methylidene]furan…
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