Apoptosis : an international journal on programmed cell deathFerroptosisHumansIntervertebral Disc DegenerationMesenchymal Stem CellsMesenchymal Stem Cell Transplantation
Multi-layered integrated shielding: engineering ferroptosis-resistant mesenchymal stem cells for precision therapy of intervertebral disc degeneration.
Yuzhu Xu, Zhanyang Qian, Mingliang Ji, Jun Lu
Published: 202610.1007/s10495-026-02273-7
Abstract
INTRODUCTION: Intervertebral disc degeneration (IVDD) is a predominant cause of low back pain, and mesenchymal stem cell (MSC) transplantation represents a promising therapeutic strategy. However, its efficacy is severely limited by the harsh oxidati…
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