Annals of biomedical engineering
Systemic Treatments Impact Bone Quality in a Preclinical Model of Mixed Femoral Metastases.
Azin Mirzajavadkhan, Leanna E Abraham, Margarete K Akens, Michael Hardisty, Cari M Whyne
Published: 202610.1007/s10439-025-03967-w
Abstract
Skeletal metastases disrupt bone remodeling, compromising mechanical integrity and increasing fracture risk. Cancer therapies can further influence bone quality. This study aimed to evaluate the impact of systemic cancer therapies (docetaxel (DTX) an…
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