International journal of clinical oncology
Intratumoral heterogeneity and chemotherapy-induced alteration of CLDN18.2 expression in resectable gastric cancer.
Shinnosuke Nagano, Yukinori Kurokawa, Takaomi Hagi, Yuichi Motoyama, Takuro Saito, Tsuyoshi Takahashi, Kota Momose, Kotaro Yamashita, Koji Tanaka, Tomoki Makino, Kiyokazu Nakajima, Eiichi Morii, Hidetoshi Eguchi, Yuichiro Doki
Published: 202610.1007/s10147-026-02972-w
Abstract
BACKGROUND: Claudin-18 isoform-2 (CLDN18.2) is a novel biomarker and therapeutic target for gastric cancer (GC). It may exhibit the intratumoral heterogeneity and varying expressions between biopsy and surgically resected specimens as well as pre- an…
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