International journal of clinical oncology
Molecular analysis of tumor recurrence using established cancer stem cell-line and drug discovery.
Kiyotaka Nakano, Eiji Oki, Masaki Yamazaki, Masami Suzuki, Shigeto Kawai, Yoko Zaitsu, Chiyoko Nishime, Koji Ando, Genta Nagae, Norifumi Harimoto, Mitsuhiko Ota, Tetsuro Kawazoe, Kentaro Nonaka, Keita Natsugoe, Sachie Omori
Published: 202610.1007/s10147-025-02948-2
Abstract
Despite advances in adjuvant therapy for colorectal cancer, tumor relapses, often driven by minimal residual disease, remain a formidable clinical challenge. The cancer stem cell hypothesis provides a key framework for understanding this problem, pos…
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