International journal of clinical oncologyHumansFemaleMutL Protein Homolog 1Endometrial NeoplasmsDNA Methylation
Prognostic and clinicopathological implications of mismatch-repair deficiency and MLH1 promoter methylation status in endometrial carcinoma.
Mayuko Goda, Gou Yamamoto, Katsuya Iuchi, Koji Horie, Kiwamu Akagi
Published: 202610.1007/s10147-025-02913-z
Abstract
OBJECTIVE: The prevalence of MSI-H and MLH1 promoter hypermethylation (MLH1-PHM) as well as Lynch syndrome in Japanese patients with endometrial cancer (EC) has not been fully revealed. There is also a recent report that the prognosis of MLH1-PHM is…
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