Neurosurgical reviewHumansGlioblastomaRandomized Controlled Trials as TopicBrain NeoplasmsImmune Checkpoint Inhibitors
Efficacy and safety of immune checkpoint inhibitors and mTOR inhibitors as targeted therapy for glioblastoma: A systematic review and meta-analysis of randomized clinical trials.
Emilio García Gómez, Miguel Angel Morales Morales, Daniel San-Juan, Juan Romero-Valencia, Dan Lisandro Romero Mendez, David Omar Lopez Hernandez, Mauricio Medina Pizarro, Edgar Ruben Barajas Narvaez, Mallyolo Eliezer Pelayo-Salazar, Sergio Moreno Jimenez
Published: 202610.1007/s10143-025-04043-6
Abstract
Glioblastoma (GB) is the most common and aggressive malignant brain tumor in adults, with poor long-term survival despite standard treatment. Targeted therapies such as immune checkpoint inhibitors (ICIs) and mTOR inhibitors have been explored to imp…
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