Neurosurgical reviewHumansDelayed-Action PreparationsDrug ImplantsNicardipineRandomized Controlled Trials as Topic
Efficacy and safety of nicardipine prolonged-release implants in patients with aneurysmal subarachnoid hemorrhage: A meta-analysis of randomized controlled trials.
Ocílio Ribeiro Gonçalves, Luís O S Nogueira, Mariana Letícia Bastos de Maximiano, Lucas Cael Azevedo Ramos Bendaham, Victor Arthur Ohannesian, Claudio Lucca Lima Furtado, Kenzo Ogasawara Donato, Lídia Santos Oliveira, Milene Vitória Sampaio Sobral, Sofia Daher Pimentel, Márcio Yuri, Gustavo Sousa Noleto, David Langer, Christian Ferreira, Yafell Serule
Published: 202510.1007/s10143-025-03892-5
Abstract
Cerebral vasospasm (CV) is a major complication following aneurysmal subarachnoid hemorrhage (aSAH), significantly contributing to morbidity and mortality. Nicardipine Prolonged-Release Implants (NPRI) offer targeted, localized drug delivery to preve…
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