Functional & integrative genomicsAnimalsExosomesDiabetic NephropathiesRNA-Binding ProteinsHumans
Epigenetic silencing of MSTN via m6A modification underlies the renoprotective effects of engineered MSC exosomes with RBM15 depletion in diabetic nephropathy.
Qianlan Dong, Longhao Dong, Yanting Zhu, Xiaoming Wang, Xiaohui Yan
Published: 202510.1007/s10142-025-01746-3
Abstract
Diabetic nephropathy (DN) is a leading complication of diabetes mellitus. Engineered exosomes have shown promise in disease treatment by enabling targeted cargo delivery. RNA-binding motif protein 15 (RBM15) accelerates the progression of DN. This st…
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