Functional & integrative genomicsDEAD-box RNA HelicasesHumansLiver NeoplasmsCarcinomaHepatocellular
DDX1 facilitates lenvatinib resistance in hepatocellular carcinoma through regulating ephrin-A3 and activating the Wnt/β-catenin signaling pathway.
Shenglan Huang, Hua Wang, Shumin Fu, Fei Cheng, Kan Liu, Jianbing Wu
Published: 202510.1007/s10142-025-01719-6
Abstract
Background Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide. Lenvatinib is a common first-line treatment for advanced HCC. However, resistance to lenvatinib is the greatest challenge limiting its clinical…
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