International microbiology : the official journal of the Spanish Society for MicrobiologyGlutamate DecarboxylaseSilicon DioxideNanoparticlesEnzymesImmobilized
Physical entrapment of glutamic acid decarboxylase from Lactobacillus casei IIB-09 in multifunctional mesoporous silica nanoparticles for controlled release of ɣ-aminobutyric acid in anxiety disorders.
Javaria Zafar, Sikander Ali, Rukhma, Tariq Aziz, Ashwag Shami, Maher S Alwethaynani, Fakhria A Al-Joufi, Ibrahim Faisal Halawani, Abdullah A Alqasem, Ahmad A Alghamdi, Reham M Mashat, Majid Alhomrani
Published: 202510.1007/s10123-025-00736-6
Abstract
Gamma-aminobutyric acid (GABA) is a sedative drug capable of alleviating anxiety disorders, but its synthetic preparation is characterized by poor stability and insufficient bioavailability, along with its high cost. In this study, its precursor glut…
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